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If significant fibrosis is confirmed, patients should be referred to a specialist to perform liver biopsy and confirm the diagnosis histologically ( Chronic inflammation is the driving force for the onset and progression of fibrosis in NASH ( 4

Landi, S

Studies demonstrate rapid systemic uptake and targeted activity at endothelial and fibroblastic levels, implicating it in nitric oxide modulation, collagen synthesis, and vascular repair

Translation to human clinical application remains limited

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